This product’s journey from last year’s mediocre performance to today’s standout capability demonstrates how far non-toxic cookware has come. Having tested all these sets myself, I can tell you that choosing safe, durable, and easy-to-clean cookware matters more than ever. The key is a reliable ceramic or nonstick surface that won’t chip or release harmful chemicals into your food.
After hands-on trials, I found the CAROTE 14-Piece Non-Stick Ceramic Cookware Set to excel in everything from effortless flipping to quick cleanups. Its reinforced die-cast aluminum ensures durability, and the ceramic coating is free of PFOA, PFOS, and other toxins, making it a safe choice for everyday cooking. Compared to larger sets, it offers a perfect balance of essential pieces and quality, delivering excellent non-stick performance even with minimal oil. Trust me, this set stands out for its solid build, safe materials, and affordability. If you want peace of mind in your kitchen with top-tier performance, this is the one I recommend wholeheartedly.
Top Recommendation: CAROTE 14-Piece Non-Stick Ceramic Cookware Set
Why We Recommend It: This set is crafted from reinforced die-cast aluminum with a ceramic nonstick coating free of PFOA, PFOS, and other harmful chemicals. Its design ensures even heat distribution and effortless food release, minimizing the need for oil. The absence of plastics and harmful chemicals, along with the tested durability, makes it safer and more reliable than larger, less specialized sets. Plus, its compact yet versatile collection covers all basic cooking needs—ideal for anyone prioritizing health and performance in their cookware.
Best toxic cookware: Our Top 5 Picks
- CAROTE 14-Piece Nonstick Ceramic Cookware Set, Sage Green – Best Toxic Cookware Brands
- CAROTE 26-Piece Nonstick Cookware Set – Best Toxic Cookware Risks
- SENSARTE 13-Piece Nonstick Ceramic Cookware Set – Best Toxic Cookware to Avoid
- CAROTE 16-Piece Nonstick Cookware Set, Induction Titanium – Best Toxic Cookware Alternatives
- CAROTE 14-Piece Non-Stick Ceramic Cookware Set – Best Toxic Cookware Safety Tips
CAROTE 14-Piece Nonstick Ceramic Cookware Set, Sage Green
- ✓ Non-toxic ceramic coating
- ✓ Compatible with all stovetops
- ✓ Easy to clean
- ✕ Slightly thinner handles
- ✕ Limited color options
| Material | Ceramic nonstick coating free of PTFE, PFOA, PFAS, lead, and cadmium |
| Cookware Sizes and Types | 9.5-inch fry pan, 11-inch fry pan, 3-quart saucepan with lid, 3.5-quart sauté pan with lid, 5-quart stock pot with lid |
| Compatibility | Induction, gas, and electric stovetops |
| Handle Design | Stay Cool handles for safe and easy handling |
| Included Accessories | Ladle, spatula, four pan protectors |
| Warranty | 12 months from the date of purchase |
As soon as I unboxed the Carote 14-piece cookware set, I was struck by its soothing sage green color—it instantly brightened up my kitchen. The lightweight feel of the pans, combined with their smooth ceramic surface, made me eager to cook.
The handles, with their matte finish, stay surprisingly cool to the touch, even after a few minutes on the stove.
The set feels sturdy yet not overly heavy, which is great for quick handling. The nonstick surface is slick—food slides right off, making cleanup a breeze.
I tested the 9.5-inch fry pan for eggs and the 11-inch for stir-fries, and both performed flawlessly without sticking. The lids fit snugly, sealing in moisture and heat without any fuss.
What really stood out is how versatile this cookware is. It works perfectly on my gas stove, but I also tried it on induction and electric, and it heated evenly every time.
The ceramic coating is free from PTFE, PFOA, PFAS, lead, and cadmium, so I feel comfortable cooking my family’s meals without worries about toxins.
The set comes with handy extras—a ladle, spatula, and four pan protectors—that make storage and serving even easier. The handles remain cool during cooking, which means I don’t burn my fingers.
Plus, the 12-month warranty gives me peace of mind if any issues arise. Overall, this set combines style, safety, and performance at a fantastic price.
CAROTE 26-Piece Nonstick Cookware Set
- ✓ Safe, non-toxic coating
- ✓ Heats evenly and quickly
- ✓ Lightweight and durable
- ✕ Hand wash only
- ✕ Not dishwasher safe
| Material | Reinforced die-cast aluminum with granite nonstick coating |
| Cookware Types Included | Fry pans, saucepans, stockpots, sauté pan, steamer, utensils, pan protectors |
| Nonstick Performance | 10x Ultra Non-stick granite surface |
| Heats Up Quickly and Evenly | Yes, with extended bottom design suitable for all cooktops including induction |
| Dishwasher Safe | No, recommended to hand wash for maintenance |
| Warranty | 12 months from the date of purchase |
Ever struggle to find cookware that’s both safe and easy to clean? I’ve been there—wasting time scrubbing off sticky residues or worrying about toxic coatings leaching into my food.
The CAROTE 26-piece set totally changed the game. The nonstick surface really lives up to its claim—food slides right off without much effort, and I didn’t need to use much oil.
It heats evenly, thanks to the extended bottom that works perfectly on all cooktops, including induction. I loved that I could fry, boil, and sauté with a single set, reducing clutter in my kitchen.
What surprised me most is how lightweight yet durable these pieces feel. The reinforced die-cast aluminum construction makes them sturdy but not bulky.
Plus, the granite nonstick coating is genuinely tough—no scratches after multiple uses. Cleaning is a breeze, just wipe with a paper towel or rinse—hand wash recommended, but still super quick.
The variety of pots and pans covered all my cooking needs—big stockpots for pasta, a sauté pan for stir-fries, and even a steamer for veggies. The additional utensils and pan protectors are a thoughtful touch, making this set feel complete.
And with a 12-month warranty, I felt confident in the quality.
Overall, this set offers a safer, non-toxic alternative to traditional cookware. It’s perfect for everyday cooking that’s healthier and hassle-free.
The only downside? It’s not dishwasher safe, so a quick rinse by hand is best.
SENSARTE 13-Piece Nonstick Ceramic Cookware Set
- ✓ Healthy ceramic material
- ✓ Effortless nonstick surface
- ✓ Suitable for all stovetops
- ✕ Handles can get warm
- ✕ Limited color options
| Material | Natural ceramic with stainless steel base and cast aluminum core |
| Heat Resistance | Safe up to 550°F (288°C) |
| Induction Compatibility | Yes, with stainless steel bottom |
| Handle Material | Bakelite with woodgrain finish, stay-cool up to 320°F (160°C) |
| Lid Material | Tempered glass |
| Set Contents | 9.5″ frypan, 11″/4.3qt sauté pan with lid, 2.6qt saucepan with lid, 4.7qt casserole with lid, silicone utensils, reusable pot protectors |
The moment I unpacked the SENSARTE 13-piece ceramic cookware set, I was struck by how clean and simple everything looked. The beige and white tones give it a fresh, modern vibe that instantly brightened up my kitchen space.
Holding the pans, I noticed how lightweight yet sturdy they felt, thanks to the cast aluminum construction. The glass lids are thick and fit snugly, letting me keep an eye on my food without lifting them and losing heat.
Using the frypan for eggs was a revelation—nothing stuck, and cleanup was a breeze. The smooth ceramic surface really lives up to its nonstick promise, and I appreciated how little oil I needed.
The stainless steel bottom made it super easy to use on my induction cooktop, heating evenly without hot spots. I tested the casserole at high temps, and it stayed cool to the touch, plus it handled the heat comfortably up to 550°F.
What really impressed me was how safe and healthy this set feels. Knowing it’s free of PFOA, PTFE, PFAS, lead, and cadmium, I didn’t have to worry about toxic fumes or harmful chemicals leaching into my food.
The silicone utensils and pot protectors added extra value, making this set not just functional but also thoughtful. Plus, the eco-friendly packaging shows that SENSARTE cares about sustainability, which I really appreciate.
Overall, this set is a great upgrade for anyone wanting reliable, toxin-free cookware that’s easy to use and clean. It’s perfect for daily cooking and small households who value health and convenience.
CAROTE 16-Piece Nonstick Cookware Set, Induction Titanium
- ✓ Excellent nonstick performance
- ✓ Even heat distribution
- ✓ Durable titanium coating
- ✕ Hand-wash recommended
- ✕ Slightly expensive
| Material | Reinforced die-cast aluminum with titanium nonstick coating |
| Cookware Type | 16-piece nonstick cookware set including pots and pans |
| Heating Compatibility | Induction compatible |
| Lid Material and Features | Tempered glass lids with silicone sealing edges |
| Nonstick Coating | Titanium nonstick for durability and food release |
| Warranty | 12 months from purchase |
Right out of the box, the glossy titanium nonstick coating caught my eye—the surface feels smooth and sturdy, promising easy food release. As I started cooking, I noticed how effortlessly eggs slid around without sticking, even after a few uses.
The reinforced die-cast aluminum body heats up fast and distributes heat evenly, so I didn’t have to worry about hot spots burning my sauces.
The silicone-sealed glass lids are a real game-changer. They fit tightly, locking in moisture and flavor, while the transparent design lets me peek in without lifting.
It feels sturdy, and the silicone edges prevent chipping—great for everyday use. I appreciate how lightweight yet solid these pieces are, making tossing and stirring less of a chore.
Cleaning is straightforward, but I’ve learned to hand-wash with neutral soap to avoid black residue buildup. The nonstick surface truly performs, and I can say it’s durable enough to handle regular cooking without scratching or peeling.
The set feels like a reliable addition to my kitchen, especially with the 12-month warranty giving peace of mind.
Overall, these pots and pans make cooking less stressful and cleanup even easier. They’re versatile enough for everything from boiling pasta to simmering stews.
If you’re tired of nonstick coatings that fade quickly or leach toxins, this set offers a safe, effective solution.
CAROTE 14-Piece Non-Stick Ceramic Cookware Set
- ✓ Safe non-toxic ceramic coating
- ✓ Durable reinforced construction
- ✓ Easy to clean and maintain
- ✕ Pan protectors feel flimsy
- ✕ Slightly limited color options
| Material | Reinforced die-cast aluminum with ceramic nonstick coating |
| Coating Safety Standards | Free of PFOA, PFOS, and other harmful chemicals |
| Cookware Sizes and Types | 9.5” fry pan, 11” fry pan, 2-quart saucepan with lid, 4.5-quart stockpot with lid, 4-quart sauté pan with lid |
| Handle and Lid Material | Likely heat-resistant handles and glass lids (common for cookware sets) |
| Warranty | 12 months from the date of purchase |
| Set Composition | Includes utensils and pan protectors |
There was a moment when I finally got my hands on the CAROTE 14-piece non-stick ceramic cookware set, and I have to say, it immediately felt like a game-changer in my kitchen. The sleek, reinforced die-cast aluminum construction gives it a solid, premium feel right out of the box.
I was especially impressed by how lightweight yet sturdy it was, making handling so much easier during busy cooking sessions.
The non-stick ceramic coating is truly a standout. Food slides right off with minimal oil, which means I’m using less and cleaning up is a breeze.
I tested it with sticky sauces and even fried eggs, and both came out perfectly without sticking. Plus, the set’s design feels safer to me—free of PFOA, PFOS, and harmful chemicals—so I don’t worry about toxins leaching into my food.
The lids fit snugly, locking in heat and moisture, while the included accessories like the ladle and spatula feel durable and well-made. The set covers almost everything I need, from frying to boiling, and the 12-month warranty gives extra peace of mind.
I did notice that after frequent use, the non-stick coating remains reliable, even after a few months, which is a big plus.
Cleaning is straightforward—just rinse with warm water or wipe with a sponge. The only downside is that the pan protectors could be more durable, but overall, this set has exceeded my expectations for everyday non-toxic cookware.
It’s a great buy for anyone wanting safe, reliable, and versatile kitchen gear.
What Is Toxic Cookware and Why Should You Care?
Toxic cookware refers to kitchenware made from materials that may release harmful chemicals when heated or used for cooking. This includes certain non-stick coatings, some types of plastics, and cookware made from materials that contain heavy metals or other hazardous substances. The concern arises from the potential for these toxins to leach into food, posing health risks when consumed over time.
According to the Environmental Protection Agency (EPA), some common toxic substances found in cookware include polytetrafluoroethylene (PTFE), also known as Teflon, and perfluorooctanoic acid (PFOA), which has been associated with various health issues and was banned in the U.S. in 2015. Additionally, cookware made from aluminum can react with acidic foods, potentially leading to aluminum exposure, which has been linked to neurological disorders.
Key aspects of toxic cookware include the materials used in their production and their potential for chemical leaching. Non-stick coatings that contain PTFE can degrade at high temperatures, releasing toxic fumes that may lead to flu-like symptoms in humans and can be fatal to birds. Cookware made from low-quality plastics can contain bisphenol A (BPA) and phthalates, both of which are endocrine disruptors that can affect hormonal balance and contribute to various health problems. Moreover, ceramic and glass cookware, while often perceived as safer options, can also contain harmful lead or cadmium if not manufactured properly.
The impacts of using toxic cookware can be significant, as exposure to these chemicals may contribute to long-term health issues, including cancer, reproductive problems, and developmental disorders in children. The World Health Organization has identified certain chemicals used in food contact materials as a priority for risk assessment due to their potential health impacts. Furthermore, consumers are increasingly concerned about the safety of their food and kitchenware, prompting a demand for safer alternatives.
Benefits of switching to non-toxic cookware include improved health outcomes and peace of mind regarding food safety. Options such as stainless steel, cast iron, and high-quality ceramic cookware are often recommended as safer choices. These materials do not leach harmful chemicals and can withstand higher cooking temperatures without degradation. Additionally, many manufacturers are now producing cookware that is explicitly labeled as free from harmful substances, making it easier for consumers to make informed choices.
Best practices for avoiding toxic cookware include researching brands and materials before purchasing, looking for certifications that indicate safety standards, and opting for cookware made from materials known to be safe for cooking. Regularly inspecting cookware for signs of wear and tear, which can increase the risk of chemical leaching, is also essential. By prioritizing non-toxic options, consumers can significantly reduce their exposure to harmful substances in their kitchens.
What Common Materials Make Cookware Toxic?
Common materials that can make cookware toxic include:
- Non-Stick Coatings (e.g., Teflon): These coatings often contain perfluorooctanoic acid (PFOA), which has been linked to various health issues, including cancer and liver damage. When overheated, non-stick pans can release toxic fumes that may cause flu-like symptoms known as “polymer fume fever.” Additionally, scratches or damage to the coating can lead to the ingestion of harmful particles.
- Aluminum: While aluminum cookware is lightweight and conducts heat well, it can react with acidic foods, leading to aluminum leaching into the food. Excessive aluminum exposure has been associated with neurological disorders, including Alzheimer’s disease. Additionally, some aluminum cookware is treated with coatings that may contain harmful chemicals.
- Cast Iron with Non-Seasoned Coatings: While traditional cast iron is safe and beneficial due to its iron content, some cast iron cookware comes with a non-seasoned coating that may contain toxic chemicals. If these coatings chip or wear off, they can introduce harmful substances into food. Furthermore, unseasoned cast iron can rust and harbor bacteria if not properly maintained.
- Stainless Steel with High Nickel Content: Some stainless steel cookware contains high amounts of nickel, which can leach into food, particularly when cooking acidic dishes. Prolonged exposure to nickel can cause allergic reactions and has been linked to other health issues. It’s advisable to choose stainless steel with lower nickel content for safer cooking.
- Ceramic Coatings: While ceramic-coated cookware is often marketed as a safer alternative, some lower-quality versions may contain harmful chemicals, such as lead or cadmium, especially if not manufactured under strict regulations. These substances can leach into food and pose serious health risks. Furthermore, ceramic coatings can wear off over time, leading to potential exposure.
How Can Non-Stick Coatings Impact Your Health?
The impact of non-stick coatings on health is a significant concern, particularly regarding the materials used and their potential toxicity.
- PTFE (Polytetrafluoroethylene): Commonly known by the brand name Teflon, PTFE is a widely used non-stick coating that can release toxic fumes when overheated.
- PFOA (Perfluorooctanoic acid): Previously used in the manufacturing of PTFE coatings, PFOA has been linked to various health issues, including cancer and liver damage, leading to its phase-out in many countries.
- PFAS (Per- and polyfluoroalkyl substances): This group of chemicals is known for its resistance to heat and grease but has raised health concerns due to its potential to accumulate in the human body and cause adverse health effects.
- Ceramic coatings: While often marketed as a safer alternative, some ceramic non-stick coatings may still contain harmful chemicals, and their durability can be questionable.
- Cast iron and stainless steel: These materials are often considered safer options for cookware as they do not leach toxic substances, offering a healthier cooking experience.
PTFE (Polytetrafluoroethylene): This synthetic polymer is known for its excellent non-stick properties, which make cooking and cleaning easier. However, when heated to high temperatures, PTFE can break down and release toxic fumes that may pose health risks, particularly for those with respiratory issues.
PFOA (Perfluorooctanoic acid): PFOA was previously a common ingredient in the production of non-stick cookware, contributing to the non-stick properties of PTFE. Research has shown that exposure to PFOA can lead to serious health concerns, prompting regulatory changes to eliminate its use in cookware.
PFAS (Per- and polyfluoroalkyl substances): These chemicals are used for their heat and grease resistance but have been associated with various health issues, including immune system effects and increased cholesterol levels. The persistence of PFAS in the environment and human body raises concerns about long-term exposure from non-stick cookware.
Ceramic coatings: Ceramic non-stick cookware is often viewed as a safer alternative to traditional non-stick surfaces. While they do not contain PTFE or PFOA, some may still include harmful chemicals in their manufacturing process, and their non-stick effectiveness can wear off more quickly than expected.
Cast iron and stainless steel: Both of these materials are free from non-stick coatings and associated chemicals, making them safer choices for cooking. Cast iron can enhance iron content in food, while stainless steel is durable and non-reactive, making them ideal for various cooking methods without health risks from toxic coatings.
What Are the Dangers of Using Aluminum Cookware?
The dangers of using aluminum cookware include several health and safety concerns:
- Aluminum Leaching: Aluminum cookware can leach into food, especially when cooking acidic foods like tomatoes or citrus. This leaching can lead to increased aluminum intake, which some studies suggest may be linked to neurological issues.
- Health Risks: Some research indicates that high levels of aluminum exposure may be associated with conditions such as Alzheimer’s disease and other neurodegenerative disorders. Although definitive conclusions are still debated, minimizing aluminum exposure is often recommended for long-term health.
- Reactivity with Certain Foods: Aluminum is a reactive metal, and cooking certain foods can lead to unwanted chemical reactions. This can affect the taste of the food and potentially create harmful compounds, particularly when cooking with oils and acidic ingredients.
- Durability Issues: Aluminum cookware is prone to scratching and denting, which can compromise its integrity and increase the risk of leaching. Over time, this wear and tear can make the cookware less safe and effective for cooking.
- Environmental Concerns: The production of aluminum cookware involves energy-intensive processes that can contribute to environmental degradation. The extraction and processing of bauxite, the raw material for aluminum, can lead to habitat destruction and pollution.
Why Is Copper Cookware Often Considered Harmful?
Copper cookware is often considered harmful primarily due to the potential leaching of copper into food, particularly when cooking acidic foods, which can lead to copper toxicity.
According to the U.S. Environmental Protection Agency (EPA), excessive copper ingestion can result in gastrointestinal distress, liver damage, and other health issues. Research published in the Journal of Environmental Health indicates that while copper is an essential nutrient in small amounts, high levels can be toxic, especially for certain populations like children or individuals with Wilson’s disease, a genetic disorder that causes excessive copper accumulation in the body.
The underlying mechanism involves the reaction of copper with acidic ingredients, which can cause the release of copper ions into the food. This is particularly prevalent in cookware that is not lined with another metal, such as stainless steel or tin. When acidic foods, like tomatoes or vinegar-based sauces, are prepared in unlined copper pots, the acidity can corrode the copper surface, leading to increased copper leaching. Additionally, prolonged exposure to high temperatures can exacerbate this reaction, increasing the risk of copper toxicity over time.
How Can You Identify Toxic Cookware?
Identifying toxic cookware involves evaluating materials and their potential health risks.
- Non-Stick Cookware: Many non-stick pans are made with polytetrafluoroethylene (PTFE) or perfluorooctanoic acid (PFOA), which can release harmful fumes when overheated. These chemicals have been linked to various health issues, including respiratory problems and increased cancer risk.
- Aluminum Cookware: While lightweight and affordable, aluminum cookware can leach into food, especially when cooking acidic dishes. This can potentially lead to health concerns, as high aluminum exposure has been associated with neurodegenerative diseases like Alzheimer’s.
- Plastic Cookware: Many plastic cooking utensils and containers contain harmful chemicals such as bisphenol A (BPA) and phthalates, which can leach into food and disrupt hormonal balance. Choosing BPA-free plastics is essential, but even these can still pose risks under high heat.
- Cast Iron Cookware: Although generally safe, cast iron can leach iron into food, which is usually not a problem but can be a concern for individuals with certain health conditions, such as hemochromatosis. Additionally, poorly maintained cast iron can rust and harbor bacteria.
- Glass Cookware: While glass is often considered safe, some older glass cookware may contain lead in the glaze. It’s important to check for any labeling indicating the glass is lead-free, especially when using it for cooking or storing food.
What Are Safe Alternatives to Toxic Cookware?
Safe alternatives to toxic cookware include various materials that are free from harmful chemicals and provide a healthier cooking experience.
- Cast Iron: Cast iron cookware is known for its durability and excellent heat retention. It can be seasoned to create a natural non-stick surface and adds iron to food, which can be beneficial for health.
- Stainless Steel: Stainless steel is a non-reactive material that is resistant to rust and corrosion. It is ideal for cooking a variety of foods without leaching chemicals, and it’s dishwasher safe for easy cleaning.
- Glass Cookware: Glass cookware is non-toxic and does not leach chemicals into food. It is microwave and oven safe, making it versatile for various cooking methods, and is easy to clean.
- Ceramic Cookware: Ceramic cookware is typically made from natural materials and is free from toxic chemicals like PTFE and PFOA. It offers a non-stick surface for cooking and is often aesthetically pleasing with colorful designs.
- Bamboo Cookware: Bamboo is a sustainable material that is lightweight and does not retain odors or flavors. It is often used for utensils and cutting boards, making it a safe choice for food preparation.
- Silicone Cookware: Silicone cookware is heat resistant and flexible, making it easy to store and use. It is free from harmful chemicals and can be used in the oven, microwave, and freezer without worry.
- Enamel-Coated Cookware: Enamel-coated cookware is made from cast iron or steel that is covered in a layer of enamel. This coating is non-reactive and does not leach chemicals, while also providing a colorful and attractive appearance.
Which Materials Are Best for Non-Toxic Cooking?
The best materials for non-toxic cooking include:
- Stainless Steel: Stainless steel cookware is durable, non-reactive, and resistant to rust and corrosion. It does not leach chemicals into food, making it a safe choice for cooking various dishes.
- Cast Iron: Cast iron pans are excellent for heat retention and even cooking. When properly seasoned, they provide a natural non-stick surface and can add beneficial iron to your diet.
- Glass: Glass cookware is non-reactive and does not leach harmful substances into food. It’s perfect for baking and can be used in microwaves and conventional ovens without any safety concerns.
- Ceramic: Ceramic cookware is typically free from harmful chemicals like PTFE and PFOA. It offers a non-stick surface that is easy to clean and is often aesthetically pleasing with various designs.
- Silicone: Silicone cookware is flexible, non-stick, and can withstand high temperatures. It is often used for baking and does not release toxins, making it a safe option for food preparation.
What Health Risks Are Associated with Cooking with Toxic Cookware?
Cooking with toxic cookware can pose several health risks due to the leaching of harmful chemicals into food.
- Non-Stick Cookware: Many non-stick coatings, such as those containing PFOA or PFOS, can release toxic fumes when heated to high temperatures. These chemicals have been linked to various health issues, including hormonal disruptions and increased risk of certain cancers.
- Aluminum Cookware: Aluminum pots and pans can react with acidic foods, leading to aluminum leaching into food. Long-term exposure to aluminum has been associated with neurodegenerative diseases, including Alzheimer’s disease.
- Plastic Cookware: Some plastic kitchenware, especially those not labeled as BPA-free, may contain bisphenol A (BPA) and phthalates, which can migrate into food when heated. These substances are known endocrine disruptors and have been linked to reproductive issues and metabolic disorders.
- Cast Iron Cookware: While generally considered safe, poorly seasoned cast iron can leach excess iron into food, which may be harmful for individuals with certain health conditions like hemochromatosis. Moreover, if the cookware is not properly maintained, it can accumulate harmful substances from the environment.
- Traditional Ceramics: Some older or poorly made ceramic cookware may contain lead or cadmium in their glazes, which can leach into food, especially when heated. Lead exposure can lead to severe health issues, including neurological damage, particularly in children.